The treaties acquired a substantial portion of the land area (dubbed the New Purchase) of the state of Indiana from the Miami, Delaware, Potawatomi, and others in exchange for cash, salt, sawmills, and other goods, effectively moving the northern boundary of the state from near the Ohio River to the Wabash River in the northwest and north.

In return, the U.S. government agreed to pay a sum total of $3,000 in silver annually to the Wea on a reservation the tribe had claimed earlier in the treaty.

The U.S. government also agreed to pay perpetual annuity to the Potawatomi, as well as to purchase any claim to the ceded land made by the Kickapoo.

In return, the U.S. government was to provide a country for the displaced Lenape people west of the Mississippi River; full compensation for their improvements; perpetual annuity; grants of land to individuals; and the payment of certain claims.

Jonathan Jennings, Lewis Cass, and Benjamin Parke, acting as representatives of the United States, signed the treaty.

Based on the terms of the accord, the Miami ceded territories south of the Wabash River covering a large portion of central Indiana, subsequently known as the "New Purchase", to the United States.

This tract consisted of the entire central portion of Indiana between the Wabash River and the old boundary established by the Treaty of Fort Wayne (1809).

In another tenet of the accord, the United States agreed to pay the Miami a perpetual annuity of fifteen thousand dollars.

It had a large trapezoid "bite" out of the northern boundary that became the Great Miami Reserve, and a sawtooth in the northwest where the Tippecanoe and Wabash Rivers formed a gore.