Residing in a centuries-old dilapidated farmhouse with her friend Sabine, Greta finds work transcribing therapy sessions for a local sex therapist named Om.

The book cover was designed by Jaya Miceli and features a painting by Anna Weyant of a woman falling down a flight of stairs.

"[4] Kirkus Reviews called Greta a "wonderfully off-kilter protagonist" and praised Beagin for her "artfully eccentric" writing style.

[5] Writing for the Los Angeles Times, Bethanne Patrick wrote that Big Swiss is a "timeless comedy" and "one of the funniest books of the last few years.

In March 2022, it was announced that Jodie Comer will star in and produce a limited series adaptation of Jen Beagin’s novel Big Swiss for HBO.