Highway 75 accompanies the river southward from Galena Summit, to an area north of Shoshone.

Below Ketchum, it is joined by the East Fork Wood River at Gimlet before passing by the small cities of Hailey and Bellevue.

A tributary stream, Camas Creek,[Note 1] joins the river in Magic Reservoir.

Below Magic Dam, the Big Wood River enters Lincoln County, passing by many lava beds and irrigation canals before entering Gooding County.

[1] Media related to Big Wood River at Wikimedia Commons