William Perley Annis (May 24, 1857– June 10, 1923) was a 19th-century American Major League Baseball outfielder.

Annis made his professional baseball debut in 1883, playing for the Pottsville Antharcites of the Interstate Association.

He was the son of Perley Mason Annis, a shoe maker, and Rozilla E.

He died on June 10, 1923, and was buried at Lindenwood Cemetery in Stoneham, Massachusetts.

[3] This biographical article relating to an American baseball outfielder born in the 1850s is a stub.