It is spreading shrub or climber that has mostly narrowly elliptic leaves and pendent yellow flowers arranged singly or in pairs.

Billardiera sericophora is spreading, woody shrub, becoming a climber as it ages, densely covered with silky, silvery hairs.

Flowering occurs from August to December and the mature fruit is a hairy, oblong berry 16–20 mm (0.63–0.79 in) long containing many seeds.

[2][3] Billardiera sericophora was formally described in 1853 by botanist Ferdinand von Mueller in the journal Linnaea: Ein Journal für die Botanik in ihrem ganzen Umfange, oder Beiträge zur Pflanzenkunde following its discovery during a botanical survey of Port Lincoln by Carl Wilhelmi.

[4][5] This species is endemic to the Eyre and Yorke Peninsulas in south-eastern South Australia where it grows in mallee scrub on coastal limestone and in the wheat belt.