Binucleating ligand

In coordination chemistry, a binucleating ligand binds two metals.

[1] A variety of metalloenzymes feature bimetallic active sites.

Examples include superoxide dismutase, urease, nickel-iron hydrogenase.

Many Non-heme iron proteins have diiron active sites, e.g. ribonucleotide reductase and hemerythrin.

Other binucleating ligands, where the binding compartments are dissimilar, facilitate the formation of heterobimetallic complexes.