Biomphalaria choanomphala is a medically important pest,[1] due to it being an intermediate host of the intravascular trematode genus, Schistosoma.

The snail's role as an intermediate host allows the parasite to complete its life cycle and infect humans who come into contact with contaminated water sources where it inhabits.

However, the species' role as an intermediate host for schistosomiasis makes it an important target for disease control programs.

Biomphalaria choanomphala is a part of the "Nilotic Species Complex" alongside B. alexandrina, B. angulosa, B. smithi, B. stanleyi and B.

[4] Biomphalaria choanomphala has been the subject of multiple ecological and genetic studies, which have revealed its shell morphology can vary as a result of environmental factors.