[1] It has been shown that, in fission yeast, microtubule attachment can make frequent erroneous attachments early in mitosis, which are then often corrected prior to anaphase onset by a system which uses protein kinase to affect kinetochore microtubules in the absence of astriction between sister chromatids.
[3] Although this process is not well understood, high-resolution imaging of live mouse oocytes has revealed that chromosomes form an intermediate chromosomal configuration, called the prometaphase belt, which occurs prior to biorientation.
[3] This suggests a possible cause for the elevated frequency of abnormal chromosome counts (aneuploidy) in mammals.
One mechanism involves the kinetochore meeting microtubules from the distal pole.
[4] Researchers have detached grasshopper spermatocytes from spindle fibers and moved them away from the metaphase plate via micromanipulation.