Union Station was also served by the Atlanta, Birmingham and Coast Railroad until the 1930s.

The Southern Railway, which had declined to join Amtrak, continued to use its own station several blocks to the northeast.

[4]: 310  Amtrak discontinued the Floridian in October 1979 but the Crescent has operated uninterrupted ever since.

The Birmingham Intermodal Facility, which opened in 2017, combines several modes of ground transportation in one central location: the MAX bus central station, Greyhound bus service, Megabus service, Amtrak passenger rail and the city's Zyp bike program.

The $32 million facility also includes a Birmingham Police substation, a food service area, a retail space and the Birmingham-Jefferson County Transit Authority's corporate offices.