The Centers for Disease Control (CDC), the agency responding to the zombie virus and responsible for public health and safety, is actually creating new substrains (culminating in a mosquito-transmitted variant released at the end of Deadline), killing off those developing immune responses (including Georgia, who was assassinated during the events of Feed), and frustrating research into a cure.

Shaun Mason, having discovered his immunity to the virus, is helping with Dr. Abbey's zombie research while hiding out from the CDC with the rest of the After the End Times team: Rebecca Atherton, Mahir Gowda, Maggie Garcia, and Alaric Kwong.

The agents use a week-long sleep study as a cover to remove trackers and self-destruct devices implanted in Georgia's body, but a mole exposes the EIS team.

She is left at the Agora for treatment, and the team heads back to Dr. Abbey's lab, where an EIS agent is waiting to transport them to Washington, D.C..

The survivors head to an EIS facility, where Shaun and Georgia help Ryman address the world, while Mahir orchestrates junior members of After the End Times to upload supporting evidence and blow the conspiracy wide open.

As the world comes to terms with the revelations, the EIS takes over the CDC, while Georgia and Shaun head to the wilds of Canada to escape the limelight.