[5] Padilla began modeling after an agent spotted her on the subway in Madrid[6] when she was a student at the ESIC Business & Marketing School.

[8] In February 2014, she was named "Female Model of the Year" at the 59th edition of the Mercedes-Benz Madrid Fashion Week,[9] for her elegance.

[10] That same year, after covering Telva twice[11] and Yo Dona[12] as well as appearing in an editorial for CYL Magazine, she walked the Victoria's Secret Fashion Show,[13] being the fourth Spanish model to do so after Esther Cañadas, Eugenia Silva and Clara Alonso.

[23] Padilla has extensive runway experience, walking for many brands, including: Armani, Chanel, Dior, Dolce & Gabbana, Givenchy, and Versace.

She is also a seasoned editorial model, having appeared in various international versions of Elle, Harper's Bazaar, and Vogue.