Blanco Creek is a 48.98 mi (78.83 km) long fifth-order tributary to the Frio River in Uvalde County, Texas.

According to the Geographic Names Information System, it has also been known historically as:[1] Blanco Creek rises about 5 miles southwest of Utopia, Texas in Uvalde County, Texas and then flows south-southeast to join the Frio River about 20 miles southwest of Uvalde, Texas.

[1] Blanco Creek drains 145.32 square miles (376.4 km2) of area, receives about 28.7 in/year of precipitation, and is about 13.18% forested.

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