The station is located in the center median of Commonwealth Avenue at Silber Way and Blandford Mall, about 2 blocks west of Kenmore Square, near the east end of Boston University.

[7] However, in December 2024, the agency indicated it would instead close Blandford Street by 2027 because it would not be feasible to build accessible platforms long enough for two-car trains of future new Type 10 vehicles.

[2] The pocket track is also used to short turn westbound service from the central subway, such as when the B branch is not operating due to maintenance, accidents, or weather conditions.

Run as Directed (RAD) trains, which provide additional capacity in the subway during peak periods, often operate from Blandford Street.

[2] During the closure of the Huntington Avenue subway, beginning December 28, 1985, regular scheduled service was run between Blandford Street and Lechmere.

On July 26, 1986 this reverted to RAD service, which was intensified on December 26, 1986 with use of other cutbacks (which, unlike Blandford Street, do not have pocket tracks).