A member of the Indian National Congress from Mangalore City, he was a minister in the Karnataka state government.
At St. Aloysius, he was president of the College Students' Union and also a member of the hockey team.
[1] Blasius D'Souza entered politics as a Mangalore City Council member in 1962 from Congress Party, where he served for 17 years.
In July 1991, he was appointed Law Minister of Karnataka in the Veerappa Moily government.
In November 1992, he was appointed Minister for Labour in a Cabinet Reshuffle, a position in which he served until 1994.