[1] This stramenopile exhibits significant genetic diversity and has become an organism of increasing scientific interest due to its widespread distribution and controversial role in human health.

[8] Genetic studies have identified several subtypes, each with different host specificities and potential pathogenic abilities[9] Blastocystis hominis demonstrates tremendous morphological plasticity throughout its life cycle.

[11] The granular form appears similar, but it has discrete granules within the central vacuole, which could represent metabolic products or reproductive elements.

[13] Recent electron microscopy studies have shown sophisticated interior features, such as surface coat variations and organelles that resemble mitochondrion[14] Blastocystis hominis has a multistage life cycle and is highly adaptable to a variety of host environments.

[21] Under stress conditions, such as unfavorable environmental factors or host immunological responses, the organism can generate pre-cyst stages that eventually develop into mature cysts.

[22] This complicated life cycle, with its numerous physical forms, helps the organism colonize and spread to a wide range of host species.