It was known during the Middle Ages as Bieda, an evolved form of its ancient name, which was restored in the twentieth century.

In the fifteenth century, Pope Boniface IX gave Blera to the Anguillara family, who owned it until 1572, apart from a short period from 1465 under direct Papal control.

Some remains of the town walls still exist, and also two ancient bridges, both belonging to the Via Clodia, and many tombs hewn in the rock with small chambers imitating the architectural forms of houses, and beams and rafters represented in relief.

[3] Eric Berggren and the Swedish Institute in Rome excavated a Republican period rural structure or villa at the site of Selvasecca di Blera between 1965 and 1967, with preliminary results published in 1969.

[6] The villa site is marked by a courtyard building that includes a remarkable vaulted cistern built using opus caementicium.