[15] She first ventured into acting in 2019 with a short cameo appearance in the tvN fantasy drama Arthdal Chronicles as Song Joong-ki's love interest.

Celebrities and influencers in South Korea, China, Thailand, and Vietnam replicated her "two-bow hairstyle" and makeup, which Jisoo created herself.

[17] Her "dot style", a makeup idea she originated, trended on social media platforms such as Instagram to promote the challenge among overseas fans.

[20] In 2021, Jisoo had her first leading role in the JTBC television series Snowdrop, helmed by Sky Castle's writer Yoo Hyun-mi and director Jo Hyun-tak.

[21] She played a college freshman, Eun Yeong-ro, who is held hostage by her love interest Lim Soo-ho, a North Korean agent portrayed by Jung Hae-in.

[24] On January 2, 2023, YG Entertainment announced that Jisoo would debut as a solo artist within the year and was in the process of recording music for her album.

[29] The lead single "Flower" was a commercial success in South Korea, peaking at number two on the Circle Digital Chart and remaining in the top ten for 12 weeks.

[35][36] Jisoo made a special cameo appearance as a Korean traditional fairy in the film Dr. Cheon and Lost Talisman, which was released on September 27, 2023.

[37] It was announced on August 31 that Jisoo had been cast as the lead role alongside Park Jeong-min in Coupang Play's new television series Newtopia, a drama about a zombie outbreak written by Han Jin-won, the writer of Parasite, and Ji Ho-jin and directed by Yoon Seong-hyun.

[38][39] Jisoo will also make her big screen debut in the film adaptation of the webtoon Omniscient Reader's Viewpoint, of which she is said to be a fan.

[41] On November 22, 2023, Jisoo was invested by King Charles III as an Honorary Member of the Order of the British Empire (MBE) alongside her bandmates during a special investiture at Buckingham Palace which was also attended by President of South Korea Yoon Suk Yeol.

[43] YG Entertainment subsequently confirmed on December 29 that Jisoo and the other Blackpink members agreed not to proceed with a contract with the label for individual activities.

[49] In 2019, she was ranked as the sixth most popular female K-pop idol in a survey of soldiers doing mandatory military service in South Korea.

[50] During the same year, Jisoo was the only one of two Korean singers added on the BoF 500 list, a "definitive professional index" of people shaping the $2.4 trillion fashion industry.

[51] She is also the fourth most-followed K-pop idol behind bandmates Lisa, Jennie and Rosé, achieving 79.5 million followers on the platform as of October 2024.

Women's Wear Daily, a fashion industry trade journal, revealed that Jisoo led the ranking in average engagement per post, followed by Rihanna and Kylie Jenner.

[56] In 2020, Dior's increase in sales during the COVID-19 pandemic in South Korea was also attributed to a marketing campaign with Korean pop singers, including Jisoo.

[83] On March 6, 2024, Jisoo was selected as the new face of London fashion house Self-Portrait as part of its Spring 2024 collection, making her the first musician in the campaign.

[93][94] The next March, Jisoo cemented her long-term partnership with Dior when they announced her as their new global ambassador,[95] alongside Natalie Portman and Cara Delevingne.

[63][100][101] In June 2021, Jisoo attended the Dior Resort 2022 show at Greece's Panathenaic Stadium,[102] wearing all-white linen dress by creative director Maria Grazia Chiuri.

[102] In September 2021, Jisoo attended Dior's Womenswear Spring/Summer 2022 show, held during the 2021 Paris Fashion Week at Jardin des Tuileries.

[106][107] In February 2022, Jisoo became the face of Dior's Addict lipstick collection along with fellow ambassadors Anya Taylor-Joy and Sharon Alexie.

[111] Ahead of Cartier celebrations of Trinity's centenary, Jisoo is one of the stars campaign among Yara Shahidi, Paul Mescal, Labrinth, and Jackson Wang.

[114][115] In February 2021, Line Friends announced Jisoo as their exclusive partner to design a character in mobile game KartRider Rush+, which would be released on March 19, 2021.