The novel concerns the life stories of three girls: the Irish Sarah Mackay, an Afrikaner Hanna Van der Beer and British Camilla Broughton Smith.

The book follows their journey from being brought up in Kenya, until their lives diverge and their hopes and dreams are destroyed, and their bond almost with it.

Blood Sisters was first published in paperback format in the United Kingdom on 6 October 2005 through Harvill Press.

[2] The novel has been translated to multiple languages that include German,[3] Turkish,[4] and Italian.

RTE's reviewer described it as "A fat, juicy, escapist read" which "captures the intoxicating beauty of Kenya and the danger that pulls all three girls back",[7] while a reviewer in the South African Independent Online said "Sentimental nonsense.