Future Plastic Man creator Jack Cole, then working for the Harry "A" Chesler studio, wrote and drew a number of one off-humor strips in the first issue: "Hold That Line", "Ima Slooth", "Foxy Grandpa" and "King Kole's Kourt."

[3] By issue #4, however, MLJ replaced the humor strips with more adventure and crime stories, and introduced fantasy-adventure characters such as the mythological Hercules in modern-day America (#4–8); the Doc Savage-like Doc Strong by Sam Cooper, set on a desolate Earth 100 years in the future soon after World War II had ended (#4–12); and the Green Falcon, a medieval adventurer whose feature was drawn by one of very few women then working in the comics, Ramone Patenaude (#4–15).

[3] The first superhero introduced to Blue Ribbon Comics was in the two-issue feature "Bob Phantom, the Scourge of the Underground" (#2–3), with early work by artist Irv Novick.

Next was Mr. Justice (#9–22), a ghostly superhero also created by writer Blair although mainly scripted by Charles Biro with artist Sam Cooper.

Inferno the Flame-Breather, originally a supporting character seen in Steel Sterling tales in Pep Comics, was given his own feature by writer Blair and artist Paul Reinman (#13–19).

The patriotically themed Captain Flag, created by Blair and artist Lin Streeter in #16 (Sept. 1941), completed the Blue Ribbon Comics superhero cluster.

The last two issues had features on the life of Galileo, Leonardo da Vinci, and Beethoven, and a tale about malaria in Cuba.

However, the second volume largely comprised new stories of previous MLJ/Archie characters: a Mr. Justice origin story by writers Robin Snyder, who also provided a Blue Ribbon Comics checklist over various issues of the comic's run, and Bill Dubay, with art by Trevor Von Eeden and Alex Niño in issue #2 (Dec. 1983).

On the letters page of issue #10 (July 1984), Buckler signaled another editorial change, to "more lighthearted stories", with more Simon/Kirby reprints from the early 1960s Adventures of the Fly, followed by a reprint in issue #11 (August 1984) of a Black Hood story from Archie Superhero Special Digest Magazine #2 (Aug. 1979), originally written for the unpublished Black Hood #1.

Martin L. Greim's company-hopping Thunderbunny starred in #13 (Oct. 1984), in a story also featuring Archie Comics' Mighty Crusaders superhero team.

These reprinted selected Mr. Justice, Captain Flag and Fox stories from the 1940s MLJ Blue Ribbon Comics that were then in the public domain.