[5] Outside of SNL, he has also voiced Louie Duck on Disney's DuckTales from 2017 to 2021, Panda in We Bare Bears from 2015 to 2020, and Hal the Dog in the PBS Kids series Nature Cat from 2015 to 2024.

[7] After graduation, Moynihan toured with a Shakespeare company before discovering Upright Citizens Brigade, where Amy Poehler gave him a job as a bartender for free classes.

During the summer of 2008, Moynihan featured in a national television ad campaign for ESPN Radio with Yankees broadcaster Michael Kay.

In 2015, he was a featured character, Lenny, in the romantic comedy film Slow Learners (original title Bad Boys, Crazy Girls).

From 2021 to 2022, Moynihan played interim Director of Communications Jayden Kwapis in the NBC sitcom Mr. Mayor,[13] and stars as the titular manatee in his series Loafy.

[15] In December 2021, Moynihan wrote the segment "The Holiday Pact" in DC Comics' anthology special Tis the Season to Be Freezin', starring the Flash and Captain Cold.