Located underneath Serangoon Road just after the traffic junction with Towner Road and Boon Keng Road, Boon Keng station primarily serves the Boon Keng subzone and more importantly the residents residing in the area.

The station was named after Lim Boon Keng, a Chinese physician who promoted health and educational reforms in Singapore.

The North East line (NEL) Contract 705 for the design and construction of Potong Pasir and Boon Keng stations and associated tunnels was awarded to the joint venture of Kumagai Gumi, Sembawang Engineering & Construction and Mitsui & Corporation on 23 June 1997 for $316.7 million.

The remaining portion of the building continues to be used for retail purposes today.

Art in Transit at this station (Metamorphosis by Lim Poh Teck) features a bright tropical-themed painting on the concourse level, consisting of icons of everyday life used in the past and present.