In 1996, Boots stated they were making a £7.6 million investment in the Republic of Ireland at an announcement in the Clarence Hotel; the first store opened later that year.

[2] In 1998, the Small Firm Association recommended to Boots that they should set up a company within Ireland for the Irish market.

[9] The first store in Ireland opened on 8 November 1996 in the Jervis Shopping Centre, representing an investment of £3.6 million and employing 150 people.

[10] The second store was officially opened in The Square Tallaght on 17 February 1997, creating an additional 40 jobs.

[15][16][17] On 14 June 2013, the website was launched, enabling customers to purchase online.