Also banned was Joe Gedeon, a second baseman for the St. Louis Browns who had placed a bet on the game and later informed to White Sox owner Charles Comiskey in hopes of getting a reward.

WNAC made history in January 1923 by linking up with New York's WEAF for the first chain broadcast (it lasts for only five minutes), and later formed a new company known as the Yankee Network.

One of its earliest and most successful radio announcers was Fred Lang (1910–1968), hired c. 1936, who read the news for Yankee network over WNAC through World War II: Lang also did Queen for a Day, the Tell-o-test Quiz Show, and a music show with a laid back flavor leading some to credit him with pioneering the "Easy Listening" style.

The television station call letters WNAC-TV remained, and in 1968 the radio and TV operations moved to 7 Bulfinch Place, near Government Center .

A number of notable performers, especially jazz musicians, were featured in this new venue, including Louis Armstrong, Dave Brubeck, Red Garland, Erroll Garner, Billie Holiday, Charles Mingus, Charlie Parker, and Sarah Vaughan.

Much of its advertising is based on its relatively low price for a hotel in Boston in very close proximity to attractions including Boston University, Charles River Reservation, the Emerald Necklace (especially Commonwealth Avenue Mall and the Back Bay Fens), Fenway Park, the Freedom Trail, Hynes Convention Center, the Isabella Stewart Gardner Museum, Lansdowne Street (home to entertainment venues including House of Blues), Newbury Street and the Prudential Center.Kenmore Station, a subway stop on the Green Line that also has an above-ground bus terminal, is located on an adjacent city block and is the hotel's closest MBTA station.

In March 2020, the hotel announced on its Facebook page that it was closing due to the COVID-19 pandemic with no plans of reopening under the current management.