The campus is situated in the South End neighborhood of Boston, Massachusetts, United States.

In conjunction with the Charles River Campus, BUMC provides the Boston University Shuttle (BUS) to transport students, staff, and faculty between campuses.

Public Safety officers provide motorist assistance, lost and found, and night escort service for the campus.

Officers on campus respond to high-stress and emergency situations on a daily basis and make frequent arrests of violators within and around the campus.

The public safety department conducts investigations for violations of University and/or Hospital policies and procedures, and suspected criminal acts.