The university rector, Dr. Casimir Stepkowskiego, writing in 1756, provided five thousand PLN for preliminary work to create a garden.
[2] [3] After the dissolution of the Order, it was transferred to the Commission of National Education, which is part of the reform of the Kraków Academy established a botanical garden as an auxiliary unit of the Faculty of Chemistry and Natural History.
The area covers about 2.4 hectares initially designed as a French baroque park within which decorated collection of medicinal plants and ornamentals.
The earliest greenhouse complex "Victoria", part of which is with the oldest glasshouse was rebuilt in the nineteenth and twentieth centuries, and was again reconstructed in 1993–1998.
Residence surrounded by geometric, quartered park in the southern part of the canal ran from the old oxbow lakes.
Reconstruction of the building for the Observatory was designed by the architect of Warsaw Stanislaw Zawadzki, and watched over its implementation Feliks Radwanski .
Construction got on the roof of the dome observation ("postrzegalnie"), and high rooms on the ground floor was used as the Botanical Gardens (including its directors lived there).
Since the mid-nineteenth century, mainly because of botanist Joseph Warszewicz (1812–1866) travel to the Central and South America, it begins to be developed collection of plants and orchids.
Since 1991 he is the director Bogdan Zemanek, for which management was carried out repairs greenhouses, boilers, College Śniadeckiego and side buildings.
On 26 May 1983, during the celebrations of the 200th anniversary jubilee of the Botanical Garden, opened a permanent exhibition written by Alicia Zemanek and George Świecimskiego artistic project.
In 1983, he established a nationwide Botany Section of the History of Polish Botanical Society, with its registered office and research program coupled with the activities of the museum.