He was also the third man to progress to the main draw of all four majors through qualifying in one year, the others being Elias Ymer in 2015 and Frank Dancevic in 2011.

[4] In 2022, Van de Zandschulp reached his maiden ATP Tour final at the Bavarian International Tennis Championships.

[3] He also qualified for the second major in 2021 and in his career at the French Open and reached the second round for his first Grand Slam win with a defeat over No.

On June 23, 2021, he was upgraded to the main draw at Wimbledon, for his third major debut in a row in 2021, as a lucky loser following the late withdrawal of the 4th seed Dominic Thiem.

[11] As a result, he improved 55 spots in the singles rankings, entering the top 100 for the first time in his career at world No.

At the 2021 St. Petersburg Open, Van de Zandschulp entered as a qualifier and beat Yoshihito Nishioka, Sebastian Korda, and for the biggest win in his career so far, world No.6 and top seed Andrey Rublev in the quarterfinals.

Van de Zandschulp reached the third round in Indian Wells, where he beat Tennys Sandgren and scoring his second top 10 victory over world no.

Seeded eight in Munich, Van de Zandschulp defeated Brandon Nakashima and Egor Gerasimov to reach a third ATP Tour-level quarterfinal in 2022.

Next, he upset second seed Casper Ruud in straight sets to reach the semifinals,[27][28] where he beat 7th seed Miomir Kecmanović in a nearly three-hour match[29][30] to become the first Dutch male player to reach an ATP Tour-level singles final since Robin Haase at Gstaad in 2016.

[32] He saved three match points at the Madrid Open to advance to the second round for the first time at this Masters against Pablo Carreño Busta.

[36][37][38] Seeded sixth, Van de Zandschulp played his first grass tournament on home soil at s'Hertogenbosch, where he lost to Emil Ruusuvuori in three sets.

The following week at Queen's Club, he reached the first ATP 500 semifinal of his career by defeating qualifier Paul Jubb, Grigor Dimitrov and Alejandro Davidovich Fokina.

[42] At the 2022 Winston-Salem Open he reached his third tour-level semifinals of the season defeating 10th seed Benjamin Bonzi in straight sets with two tiebreaks.

[43] In October, he reached second round of Astana Open, where he lost in straight sets to the eventual champion, Novak Djokovic.

[52] In March, seeded 28th at the Indian Wells Masters, he retired during his second-round match against Ilya Ivashka.

In April, seeded fourth this time in Munich, van de Zandschulp defeated Aslan Karatsev and Marcos Giron to reach the semifinals.

In mid April, after a loss in the second round to fourth seed Jan-Lennard Struff, he left the top 100 in the rankings, unable to defend his runner-up points at the 2024 BMW Open in Munich.

[citation needed] At the US Open he reached the second round for a fourth consecutive year with a win over Denis Shapovalov.

1 and US Open champion Carlos Alcaraz in straight sets, ending his 15 match Grand Slam win streak.

[64] On 22 November, van de Zandschulp helped the Netherlands reach the final at the 2024 Davis Cup for the first time in their country’s history, first he retired Nadal and afterwards he and Tallon Griekspoor defeated Germany in the two singles matches.