[7] However, following Smith's description, B. hamorii continued to be misidentified as B. smithi until the situation was clarified by J. Mendoza and O. Francke in 2017.

When viewed retrolaterally, the palpal bulb of B. hamorii is narrower and less straight than the broad, spoon-shaped one of B. smithi.

In 2017, Mendoza and Francke showed that although B. hamorii and B. smithi are similar in external appearance, they are clearly distinguished by their DNA barcodes.

Molting serves several purposes, such as renewing the tarantula's outer cover (shell) and replacing missing appendages.

Like most New World tarantulas, B. hamorii specimens kick urticating hairs from their abdomens and back legs if disturbed, rather than bite.

They are only slightly venomous to humans and are considered extremely docile; however, as with all tarantulas, their large fangs can cause very painful puncture wounds, which can lead to secondary bacterial infection if not properly treated, and allergies may intensify with any bite.

It constructs or extends burrows under logs, rocks, and tree roots, among thorny shrubs and tall grass.

The deep burrows keep them protected from predators, such as the white-nosed coati, and enable them to ambush passing prey.

The females spend the majority of their lives in their burrows, which are typically located in, or not far from, vegetation, and consist of a single entrance with a tunnel leading to one or two chambers.

The tunnel, usually about three times the tarantula's leg span in length, leads to a chamber that is large enough for the spider to safely molt.

When the tarantula needs privacy, e.g. when molting or laying eggs, the entrance is sealed with silk, sometimes supplemented with soil and leaves.

[11] The reasons for these actions seem to be an irrational fear based on myth surrounding B. hamorii and related species.

[12] Large numbers of Mexican redknee tarantulas caught in the wild continue to be smuggled out of Mexico.