A water tower on the site of the former freight yard and a plaque commemorating French forced labourers at the station buildings are heritage-listed.

[1] The station is located at the kilometre 61.3 point of the Berlin–Magdeburg railway (calculated from the former Berlin Potsdamer Bahnhof), which runs in an approximately east–west direction.

The West Havelland District Railway (Westhavelländische Kreisbahnen) line (opened in 1901 and closed in the 1960s) did not reach the main station.

Brandenburg was formerly a stop for long-distance trains, many of which ran from Berlin via Magdeburg and continued to western and southern Germany.

After the fall of the Berlin Wall, trains to western and southern Germany began to stop in Brandenburg again.

With the commissioning of the Hanover–Berlin high-speed railway, long-distance passenger services shifted predominantly to that line and no longer went through Brandenburg.

The platforms are connected with one another and with the station forecourt on the north side of the tracks by a tunnel, although there is no direct access from the south.

In the western part of the station are connecting tracks for traffic to/from the Brandenburg Towns Railway.