He has been a member of the Detroit Lions, Atlanta Falcons, Buffalo Bills, Miami Dolphins, and the Los Angeles Rams.

[3] On December 30, Powell started in place of Kenny Golladay and caught six passes for 103 yards against the Green Bay Packers.

[11] On December 26, 2021, in a game against the Minnesota Vikings, Powell returned a punt 61 yards for a touchdown that was key in the Rams' victory, ensuring a playoff berth for the team.

He was named National Football Conference Special Teams Player of the Week for the first time in his NFL career for his performance.

[16] He served as the team's primary punt returner in 2023 and also put up career receiving numbers with 29 catches for 324 yards and one touchdown.