[2]: 1345 In the United States, both the Federal Trade Commission and the Food and Drug Administration have taken action against the manufacturers of these products for fraudulent practices.
The compounds claimed to be pharmacologically active are typically estrogen mimics (called xenoestrogens; specifically known as phytoestrogens in plants and mycoestrogens in fungi).
[9] Commonly used ingredients include:[1]: 1330 [2]: 1345 There is inadequate scientific study whether herbal breast enlargement can be safely achieved.
[2]: 1348 In the United States, herbal products are normally sold under "generally recognized as safe" (GRAS) rules and are not approved for any indication.
Indirect assay tests of the product Erdic (also known as Bust out) on the uterus of rodents, by measuring the amount of estrogen present, showed no difference from the control.