Brendan Scott Crabb (born 13 September 1966) is an Australian microbiologist, research scientist and director and chief executive officer of the Burnet Institute, based in Melbourne, Victoria, Australia.

This discovery was published in Nature and solved the mystery of how proteins with an export motif are trafficked out of the infected parasite and into the cytosol of the red blood cell host.

[4] Together with his principal collaborator Alan Cowman, Crabb is also well known for his development of molecular genetic systems in human malaria, having described the first gene knockout in the causative agent Plasmodium falciparum in a paper published in the journal Cell.

He has led research strategies to support responses in Melbourne and internationally; especially in the areas of diagnostic test and vaccine development, epidemiology and modelling, and through community-based approaches to improve uptake of interventions.

Although a molecular scientist by training, Crabb's interests include addressing technical and non-technical barriers to maternal, newborn and child health in the developing world.