The Brenham Heritage Museum is a local history museum in downtown Brenham, Texas located in the former US Post Office-Federal Building-Brenham listed on the National Register of Historic Places building.

A non-profit was established, collections were acquired, funds were raised and the museum opened soon after.

A number of individuals and organizations have provided the museum with significant portions of the collection.

[3][4] The artifacts tell the story of Washington County, from German immigrant settlement to its development as an agricultural and industrial center.

[7] Listed on the National Register of Historic Places in 1990, it was added due to its notable Classical Revival architecture.