[5] Along with Gary Barnidge of the Cleveland Browns, Giacomini founded American Football Without Barriers in 2011, a football-related charity foundation.

[6] The son of two Brazilian expatriates from Governador Valadares,[7] Giacomini was born in Cambridge, Massachusetts and raised in Malden.

His interest in playing football began as Giacomini was brought to meet New England Patriots quarterback Drew Bledsoe at the Boston Marriott, where his father worked.

He started his freshman and sophomore years, but decided not to play football as a junior to concentrate on basketball, as he averaged 21.0 points per game as a senior and was second in the league in scoring.

Giacomini ultimately committed to play for Louisville, which was the lone Division I-A college program to offer him a scholarship.

[10] While he had played on the defensive side of the ball in high school, the Louisville coaches were so impressed with his speed and catching ability they converted him to a tight end for his freshman and sophomore seasons.

[29] On March 22, 2018, Giacomini signed with the Oakland Raiders, reuniting with former Seahawks offensive line coach Tom Cable.