He has also worked with artists such as Levon Helm & The Midnight Ramble Band, Bob Dylan, BB King, Al Green, Dolly Parton, Buster Poindexter, and Allen Toussaint.
He also cowrote the music for the AMC TV series Hell On Wheels with Marc Copely and James Dolan and recently, the song "Step Away" written by Mitchell and Christine Santelli was included on Bettye LaVette's Grammy nominated CD "Worthy".
Other special collaborations include accompanying actor Christopher Walken on accordion in the movie "Search and Destroy" and playing piano with Amy Helm in the Vera Farmiga directed film "Higher Ground".
Mitchell performed with Levon Helm in the Grammy award-winning DVD Live At The Ryman along with Robert Plant, Steve Earle, Emmylou Harris, Buddy Miller, and Sheryl Crow.
On April 22, 2017, Mitchell performed on PBS once again with The Weight Band on "Live At The Infinity" and in November 2017, he appeared at The Woodland Festival in Namsos, Norway as the featured accordionist.