Unusually for Bristol, a slightly revised version was launched during the middle of the model's production run in 1965 and known as the 408 Mark II.

The frontal styling of the 407 – which had been a carry-over from the six-cylinder 406 – was discarded and in its place was a rectangular grille with pronounced horizontal bars.

Due to safety concerns, the push-button layout of the automatic transmission was modified through the use of a safety lever to prevent an unwary person moving the car out of "Park".

There were also rectangular instead of circular push-buttons for the gear selector in this version of the car.

The transmission itself was now of cast alloy and was over 30 kg (66 lb) lighter than that of previous eight-cylinder Bristols.