As one of the simplest possible stable chiral compounds, it is useful for fundamental research into this area of chemistry.

[1] However, its relative instability to hydrolysis,[2] and lack of suitable functional groups, made separation of the enantiomers of bromochlorofluoromethane especially challenging,[3] and this was not accomplished until almost a century after it was first synthesised, in March 2005, though it has now been done by a variety of methods.

[4][5][6][7] More recent research using bromochlorofluoromethane has focused on its potential use for experimental measurement of parity violation, a major unsolved problem in quantum physics.

[8][9][10] For example, the S enantiomer is predicted to be lower in energy by about 2.356×10−16 eV (56.97 mHz),[11] and the frequency of the C−F vibrational mode should be about 2.4 mHz lower for the R-enantiomer.

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