[1] BAMC is staffed by more than 8,000 soldiers, airmen, sailors, civilians, and contractors, providing care to wounded service members and the San Antonio community at large.

In 1941, the Station Hospital prepared for an overwhelming flow of casualties from World War II battlefields by converting a 220-person enlisted barracks into additional patient wards.

On July 18, 1995, ownership of the replacement hospital was given to the BAMC Commander by the U.S. Army Corps of Engineers during the key turnover ceremony.

As of 1 Oct 2017, the designation SAMMC was removed and BAMC continues to represent the headquarters that serves as the command for the entire hospital along with the medical clinics on Fort Sam Houston, others in the San Antonio area, and one at the Army Depot in Corpus Christi.

[4] The collaboration between BAMC and local Air Force Medical assets are governed by the San Antonio Military Health System (SAMHS).

The term SAMMC solely applies to the inpatient capabilities within the hospital at Brooke Army Medical Center (BAMC).

The USAISR Burn Center is part of the U.S. Army Medical Research and Development Command located at Fort Detrick, Maryland.

BAMC is the only MEDCOM Level I trauma center in the Department of Defense, and is part of the Regional Health Command Central (RHC-C).

To accomplish the realignment of inpatient services and related specialty care from Wilford Hall Medical Center (WHMC) to Brooke Army Medical Center (BAMC) as presented in the BRAC 2005 scenario, BAMC will undergo the construction of a consolidated tower, a parking facility, a central energy plant, and renovations within the existing facility.

[needs update] Due to the size increase in the BAMC facility, additional heating and cooling capacities are being provided with a 22,400-square-foot (2,080 m2) central energy plant, which is under construction.