He is best known, together with Michael Dante DiMartino, as the co-creator and executive producer of the animated series Avatar: The Last Airbender and The Legend of Korra.

Between 2001 and 2014, Konietzko, together with Michael Dante DiMartino, was mainly occupied with writing and producing the animated series Avatar: The Last Airbender and its sequel The Legend of Korra for Nickelodeon.

[1] As of 2015, Konietzko was working on writing and illustrating a sci-fi graphic novel series, Threadworlds, that is to be published by First Second Books, but there is no release date.

[2] In September 2018, Netflix announced that Konietzko and DiMartino would serve as executive producers and showrunners for the live-action series based on Avatar: The Last Airbender, which released in 2024.

[3] On August 12, 2020, Konietzko and DiMartino revealed on social media that they had both departed the show, due to creative differences with the Netflix team.