Initially, the ill people were taken care off by sisters and brothers of the order of the Cistercians, but later on, they oriented towards the rules of Saint Augustine.
Nowadays, the hospital is part of the larger AZ Groeninge and is called campus Reepkaai.
When the English Allies left the city in 1918 and 1940, they destroyed the bridges, which caused severe damage to the houses around it.
During a friendly fire on 26 March 1944, 8 houses on the southern banks were destroyed and two people were killed.
During the first half of the 20th century, the Buda island was enlarged on the northern side, because the River Leie was moved in order to facilitate the passage of ships.