The Burgess-Maschmeyer Mansion is a historic residence at 1209 Government Street in the Oakleigh Garden Historic District of Mobile, United States.

It was built in 1907 in the Renaissance Revival style by noted Mobile architect George Bigelow Rogers.

The residence was constructed for cotton factor Col. David R. Burgess.

After his death in 1917, it was inherited by his daughter Ethel Burgess Maschmeyer.

It subsequently was transferred to the University of Mobile to be used as its President's home.