Burst Angel takes place in the near future, after a rise in criminal activity forced the Japanese government to allow citizens to possess firearms and establish the Recently Armed Police of Tokyo (RAPT).

The story opens with Kyohei Tachibana, a male college student at a culinary arts school with dreams of someday becoming a pastry chef, motorcycling down an inner city street and becoming caught up in a shoot-out between a mysterious silver-haired woman and a psycho gangster.

Kyohei escapes unharmed and ends up working as a cook for Jo, Meg, Amy, and Sei in an effort to gather up enough money to travel to France.

Burst Angel focuses on the group as they investigate a series of mutated human monsters with glowing brains that cause various amounts of mayhem in Tokyo.

[4] Burst Angel, animated by Gonzo, directed by Koichi Ohata and written by Fumihiko Shimo, was broadcast for twenty-four episodes on TV Asahi from April 7 to September 22, 2004.

The OVA deals is a side story revolving around Jo and Meg visiting Sam and her old gang in New York explaining the aftermath of episode 14 of the TV series.