The facility, which was designed by architect Edward Holmes, opened in October 1869.

[1] The infirmary's first President was the Marquess of Anglesey who also had been the previous owner of the site.

[1] It was expanded to a design by Aston Webb in 1899 in such a way that the building extended right back to New Street.

[2] Following further expansion in 1924, 1931 and 1942,[3] it joined the National Health Service in 1948.

[4] After services had been transferred to Queen's Hospital, the ageing infirmary closed in 1993; the buildings were demolished in 1994 and the site was redeveloped for residential use.