It replaced an older dispensary between Bury Lane and Bolton Street.
Sometime in the 20th-century, a children's ward was built to the left hand side of the site.
This was because of the poor condition of the then 92 year old building and its limited bed capacity.
In 1998, the Authority commissioned a £24 million extension to the Fairfield General Hospital complex.
After the works were complete, the accident and emergency centre moved to Fairfield General Hospital in September 2001.