The game was released digitally, for Microsoft Windows on 22 March 2007, and for OS X on 8 June 2011.

A port to iOS, entitled Bus Driver – Pocket Edition, was released to the App Store by Meridian4 on 27 February 2014.

In total, there are six tiers, thirty-six routes and thirteen buses (seventeen in Temsa Edition).

The player will lose points if they disobey traffic laws (going out of lane without using blinkers, driving on the wrong side of the road, hitting other vehicles, hitting obstacles like streetlamp), upset passengers (by braking too hard or causing accidents) or they depart from the bus stop too early, honking at the passengers to make them board faster at the bus stop or even if they leave passengers waiting at a bus stop.

Conversely, the player will gain points for obeying traffic laws, safe driving and being punctual.

[1] Despite being a game set in the United States, many of the bus stop names and cities are named after areas of London, including Debden, Collier Row, Feltham, Potters Bar and the terminus Westminster.

As a game set in the United States, most of the buses are based on American designs, however, there are some which are based on European designs since the game was made in the Czech Republic.

The buses included are 3 MCI 102D3 (known as GNR-13 LE, including a jail variant which is known as GNR-13 Eco), a Ford B-Series school bus (known as Toucan), a MCI D4500 coach (known as Gryphon Birdie), 2 NovaBus RTS-06 (known as Niva WS-27 Cityroamer), 2 Setra S415HDH (known as Sista XT), 2 Renault Agora S (known as Remark EU) and a Volvo B7TL Wright Eclipse Gemini double decker (known as Velven 18).