The college traces its origins to the merger of several institutions, which became public in 1967 when the Quebec system of CEGEPs was created.

On April 15, 1968, les Corporations de l'Externat Classique Saint-Raphaël et du Collège Marie-de-la-Présentation partnered for the school year 1968–1969.

In 1972, a partnership of CEGEPS from Drummondville, Saint-Hyacinthe and Sorel formed le Collège régional Bourgchemin.

In 1980, the government of Quebec granted a charter of Cégep de Drummondville, and the CEGEP opened its doors on May 13, 1980 – 1981, with 1171 students in pre-university teaching and 475 in continuing education.

In 2006, Cégep de Drummondville counted 1900 students with pre-university teaching and nearly 200 in continuing education.