Cần Đước is a rural district (huyện) of Long An province in the Mekong River Delta region of Vietnam.

At the beginning, Cần Đước was a small village located in a peninsula created by the Mương Ông Quỳnh and Rach Ben Ba distributaries.

Trương Định refused to recognise the treaty and continued guerrilla attacks against French patrols and their Vietnamese collaborators.

After the death of Trương Định on August 19, 1864, Cần Đước became part of another guerrilla campaign against the French authority which was led by Nguyễn Trung Trực.

In the early 20th century, Cần Đước became part of many nationalist movements such as Thiên Địa Hội or the Nguyễn An Ninh society.

After the end of the First Indochina War, Cần Đước became a county part of Chợ Lớn Province in 1954 under the new state of South Vietnam.