CASP

Even though the primary goal of CASP is to help advance the methods of identifying protein three-dimensional structure from its amino acid sequence many view the experiment more as a "world championship" in this field of science.

[6] Free modeling (template-free, or de novo) is also evaluated visually by the assessors, since the numerical scores do not work as well for finding loose resemblances in the most difficult cases.

Due to limited numbers of template free targets (they are quite rare), in 2011 so called CASP ROLL was introduced.

Unlike LiveBench and EVA, this experiment is in the blind-prediction spirit of CASP, i.e. all the predictions are made on yet unknown structures.

[18] According to one of CASP co-founders John Moult, AlphaFold scored around 90 on a 100-point scale of prediction accuracy for moderately difficult protein targets.