It primarily localizes to the centrosome, a non-membraneous organelle that functions as the major microtubule-organizing center in animal cells.

Furthermore, it increases the stability of growing centrioles.

[8] It is also implicated in the regulation of a class of nuclear hormone receptors in the nucleus.

Several alternatively spliced transcript variants have been found, but their full-length nature has not been determined.

This article on a gene on human chromosome 1 is a stub.