[1] Examples include: Since the neural impulse is inhibited in this condition it may lead to paresthesia, muscle weakness, unsteady gait, paralysis, vision loss and other motor dysfunctions.

CNS demyelination autoimmune disease causes the myelin sheath to deteriorate since the sense of recognition of self is lost.

The loss of the myelin insulation either disrupts or prevents neural conduction along the nerve cell's axon.

The brain and the spinal cord are the essential components of the central nervous system and it is responsible for the integration of the signals received from the afferent nerves and initiates action.

These microscopic nerve fibers, where the action potential occurs, are protected by a white, fatty tissue that surrounds and insulates it, known as the myelin sheath.