[5] This gene encodes a member of a family of cytosolic phosphoproteins expressed exclusively in the nervous system.

The encoded protein is thought to be a part of the semaphorin signal transduction pathway implicated in semaphorin-induced growth cone collapse during neural development.

Alternative splicing results in multiple transcript variants.

[5] CRMP1 mediates reelin signaling in cortical neuronal migration.

This article on a gene on human chromosome 4 is a stub.